PMS2 Mouse Monoclonal Antibody [Clone ID: 163C1251]

CAT#: TA336401

Mouse Monoclonal PMS2 Antibody (163C1251)

Product Images

Western Blot: PMS2 Antibody (163C1251) TA336401 - Analysis of PMS2 using this antibody at 2 ug/ml against 10 ug of NIH 3T3 cell lysate.

Specifications

Product Data

• Clone Name: 163C1251
• Applications: WB
• Recommended Dilution: Flow Cytometry: 1ug per 10^6 cells, Western Blot: 1-2 ug/ml, Immunohistochemistry: 2-5ug/ml, Immunohistochemistry-Paraffin: 2-5ug/ml, CyTOF-ready
• Reactivities: Human, Mouse
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: This antibody was generated by immunizing mice with a synthetic peptide corresponding to amino acids 623-639 SSLAKRIKQLHHEAQQS of human PMS2; GenBank No. NP_000526.1.
• Formulation: PBS containing 0.05% BSA, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Concentration: lot specific
• Purification: Protein G purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: PMS1 homolog 2, mismatch repair system component
• Database Link:
  NP_000526
  Entrez Gene 18861 MouseEntrez Gene 5395 Human
  UniProt ID P54278
• Background: PMS1 protein homologue 2 (PMS2) is a DNA mismatch repair protein. Defects in PMS2 are a cause of hereditary non-polyposis cancer (HNPCC). Human PMS2 is an amino acid protein of 862 amino acids.
• Synonyms: HNPCC4; PMS2CL; PMSL2

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Mismatch repair