SIAH2 Mouse Monoclonal Antibody [Clone ID: 24E6H3]

CAT#: TA336562

Mouse Monoclonal SIAH2 Antibody (24E6H3)


USD 457.00

5 Days*

Size
    • 500 ul

Product Images

Frequently bought together (3)
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Specifications

Product Data
Clone Name 24E6H3
Applications IHC
Recommended Dilution Immunohistochemistry-Frozen: 1:40-1:50, Flow Cytometry: 1:10, Flow (Intracellular), Immunohistochemistry: 1:40-1:50, Immunocytochemistry/ Immunofluorescence: 1:10, Western Blot, Immunohistochemistry-Paraffin: 1:40-1:50
Reactivities Human, Drosophila, Porcine (Does not react with: Mouse)
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Synthetic peptide made to an N-terminal portion of the drosophila SINA protein (within residues 1-100). [Swiss-Prot# P21461]
Formulation Preservative: 0.1% Sodium Azide. Store at 4C. Do not freeze.
Concentration lot specific
Purification Tissue culture supernatant
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name siah E3 ubiquitin protein ligase 2
Background The Drosophila SINA (seven in absentia) protein is an E3 ubiquitin ligase component of the RAS signal transduction pathway. The RAS signal pathway controls cell proliferation, differentiation, and survival, and regulation of this pathway is critical for normal development. In Drosophila SINA serves as a downstream gatekeeper required for proper RAS signal transduction. Similarly to SINA in Drosophila, the human protein SIAH has also been shown to be required for oncogenic RAS signaling in cancer.
Synonyms hSiah2
Note This SIAH2 (24E6H3) antibody is useful for Flow Cytometry, Immunocytochemistry/Immunofluorescence and Immunohistochemistry on paraffin-embedded and frozen sections.
Reference Data
Protein Families Druggable Genome, Transcription Factors

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.