AMACR Mouse Monoclonal Antibody [Clone ID: 2F3-C11-B12]

CAT#: TA346883

Mouse Monoclonal AMACR (C-terminus) Antibody

Product Images

Western blot detection of AMACR (C-terminus) in Rat Liver lysates using AMACR (C-terminus) mouse mAb (1:1000 diluted).Predicted band size: 42KDa.Observed band size: 42KDa.

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  Immunocytochemistry staining of Jurkat cells fixed with -20? Ethanol and using anti-AMACR (C-terminus) mouse mAb (dilution 1:100).

Specifications

Product Data

• Clone Name: 2F3-C11-B12
• Applications: IF, WB
• Recommended Dilution: WB: 1:1000, IF: 1:100
• Reactivities: Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: The immunogen for AMACR antibody: purified recombinant human AMACR(C-terminus) protein fragments expressed in E.coli.
• Formulation: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50%,glycerol
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 42 kDa
• Gene Name: alpha-methylacyl-CoA racemase
• Database Link:
  NP_055139
  Entrez Gene 25284 Rat
  UniProt ID Q9UHK6
• Background: This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)-and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described.
• Synonyms: AMACRD; CBAS4; RACE; RM

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Primary bile acid biosynthesis