Hexokinase II (HK2) Mouse Monoclonal Antibody [Clone ID: 3B9-F8-F10]

CAT#: TA346965

Mouse Monoclonal Hexokinase II Antibody

Specifications

Product Data

• Clone Name: 3B9-F8-F10
• Applications: WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: The immunogen for HK2 antibody: purified recombinant human Hexokinase II protein fragments expressed in E.coli.
• Formulation: PBS(pH 7.4) containing with 0.03% Proclin300 and 50% glycerol.
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 102 kDa
• Gene Name: hexokinase 2
• Database Link:
  NP_000180
  Entrez Gene 3099 Human
  UniProt ID P52789
• Background: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
• Synonyms: HKII; HXK2

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Amino sugar and nucleotide sugar metabolism, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Insulin signaling pathway, Metabolic pathways, Starch and sucrose metabolism, Type II diabetes mellitus