MSH2 Mouse Monoclonal Antibody [Clone ID: 4G5-E11-D9]

CAT#: TA347005

Mouse Monoclonal MSH2 Antibody

Product Images

Western blot detection of MSH2 in K562, CEM, Jurkat, 293T and A431 cell lysates using MSH2 mouse mAb (1:1000 diluted).Predicted band size:100KDa.Observed band size:100KDa.

Specifications

Product Data

• Clone Name: 4G5-E11-D9
• Applications: WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: The immunogen for MSH2 antibody: purified recombinant human MSH2 protein fragments expressed in E.coli
• Formulation: Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 100 kDa
• Gene Name: mutS homolog 2
• Database Link:
  NP_000242
  Entrez Gene 4436 Human
  UniProt ID P43246
• Background: This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC).When cloned,it was discovered to be a human homolog of the E. coli mismatch repair gene mutS,consistent with the characteristic alterations in microsatellite sequences (RER phenotype) found in HNPCC.Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq,Apr 2012]
• Synonyms: COCA1; FCC1; HNPCC; HNPCC1; LCFS2

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: Colorectal cancer, Mismatch repair, Pathways in cancer