RSF1 Mouse Monoclonal Antibody

CAT#: TA347275

Mouse Monoclonal Rsf1 Antibody

Product Images

WB was performed on nuclear extracts from HeLa cells (HeLa NE, 20 ug) using the antibody against hRSF1, diluted 1:1,000 in TBS-Tween containing 5% skimmed milk. The molecular weight marker (in kDa) is shown on the left), the position of the protein of interest is shown on the right.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blotting (1:1,000) ; Immunofluorescence (1:100 - 1:500); Immunoprecipitation (1 µg/IP)
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: The immunogen for anti-Rsf1 antibody: human RSF1 (remodeling and spacing factor 1), using a recombinant protein.
• Concentration: lot specific
• Purification: Ascites fluid from mouse containing 0.05% azide.
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: remodeling and spacing factor 1
• Database Link:
  NP_057662
  Entrez Gene 51773 Human
• Background: RSF1 (UniProtKB/Swiss-Prot entry Q96T23) is required for assembly of regular nucleosome arrays by the RSF chromatin remodelling complex. Rsf1 facilitates transcription of hepatitis B virus (HBV) genes by the pX transcription activator. In case of infection by HBV, together with pX, it represses TNF-alpha induced NF-kappaB transcription activation. Rsf1 represses transcription when artificially recruited to chromatin by fusion to a heterogeneous DNA binding domain. Rsf1 interacts with SMARCA5/SNF2H to form the RSF complex and also binds the HBV pX/HBx protein, which is required to activate transcription of the viral genome.
• Synonyms: HBXAP; p325; RSF-1; XAP8

Reference Data

• Protein Families: Druggable Genome