E2F4 Rabbit Polyclonal Antibody

CAT#: TA347373

Rabbit Polyclonal Anti-E2F4 Antibody

Product Images

Western blot analysis on COS7 cell lysate using E2F4 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:3000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-E2F4 Antibody: A synthesized peptide derived from human E2F4
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Affinity-chromatography
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 44 kDa
• Gene Name: E2F transcription factor 4
• Database Link:
  NP_001941
  Entrez Gene 104394 MouseEntrez Gene 100360427 RatEntrez Gene 1874 Human
  UniProt ID Q16254
• Background: E2F4 Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC- 3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F-4 binds with high affinity to RBL1 and RBL2. In some instances, can also bind RB protein. Belongs to the E2F/DP family. Component of the DRTF1/E2F transcription factor complex. Binds cooperatively with DP-1 to E2F sites
• Synonyms: E2F-4
• Note: E2F4 antibody detects endogenous levels of total E2F4

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Cell cycle, TGF-beta signaling pathway