E2F4 Rabbit Polyclonal Antibody

CAT#: TA347373

Rabbit Polyclonal Anti-E2F4 Antibody


USD 380.00

4 Weeks*

Size
    • 100 ug

Product Images

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Specifications

Product Data
Applications WB
Recommended Dilution WB: 1:500-1:3000
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen The immunogen for anti-E2F4 Antibody: A synthesized peptide derived from human E2F4
Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration lot specific
Purification Affinity-chromatography
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 44 kDa
Gene Name E2F transcription factor 4
Background E2F4 Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC- 3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F-4 binds with high affinity to RBL1 and RBL2. In some instances, can also bind RB protein. Belongs to the E2F/DP family. Component of the DRTF1/E2F transcription factor complex. Binds cooperatively with DP-1 to E2F sites
Synonyms E2F-4
Note E2F4 antibody detects endogenous levels of total E2F4
Reference Data
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Cell cycle, TGF-beta signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.