Fibroblast activation protein, alpha (FAP) Rabbit Polyclonal Antibody

CAT#: TA347770

Rabbit Polyclonal Anti-FAP-1 Antibody

Product Images

Western blot analysis on LOVO cell lysate using FAP-1 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-FAP-1 Antibody: A synthesized peptide derived from human FAP-1
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 88 kDa
• Gene Name: fibroblast activation protein alpha
• Database Link:
  NP_004451
  Entrez Gene 14089 MouseEntrez Gene 192203 RatEntrez Gene 2191 Human
  UniProt ID Q12884
• Background: PTPN13 Tyrosine phosphatase which regulates negatively FAS- induced apoptosis and NGFR-mediated pro-apoptotic signaling. Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily. Interacts with TRIP6 and TNFRSF6 (Fas receptor) through its second PDZ domain. Interacts with the C-terminal SVP motif of NGFR through its third PDZ domain.
• Synonyms: DPPIV; FAPA; SIMP
• Note: FAP-1 Antibody detects endogenous levels of FAP-1

Reference Data

• Protein Families: Druggable Genome, Protease, Transmembrane