IZUMO1 Rabbit Polyclonal Antibody

CAT#: TA349034

Rabbit Polyclonal Anti-TOPAZ1 Antibody

Product Images

Western blot analysis of TOPAZ1 in human testis tissue lysate with TOPAZ1 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.

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  Immunohistochemistry of TOPAZ1 in rat testis tissue with TOPAZ1 antibody at 5 ug/mL.

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  Immunofluorescence of TOPAZ1 in rat testis tissue with TOPAZ1 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: TOPAZ1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human TOPAZ1.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: TOPAZ1 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 65, 186 kDa; Observed: 60, 240 kDa
• Gene Name: izumo sperm-egg fusion 1
• Database Link:
  NP_872381
  Entrez Gene 284359 Human
  UniProt ID Q8IYV9
• Background: The testis and ovary specific PAZ domain containing 1 (TOPAZ1) protein is a highly conserved protein that is highly expressed in the gonads during germ cell meiosis, suggesting that it may play a role in germ cell development (1). It contains a PAZ domain and a zinc finger domain and is exclusively expressed in adult testis and fetal ovary.
• Synonyms: IZUMO; OBF

Reference Data

• Protein Families: Transmembrane