CADM3 Rabbit Polyclonal Antibody

CAT#: TA349104

Rabbit Polyclonal Anti-CADM3 Antibody

Product Images

Western blot analysis of CADM3 in mouse brain tissue lysate with CADM3 antibody at (A) 1 and (B) 2 ug/mL.

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  Immunohistochemistry of CADM3 in mouse brain tissue with CADM3 antibody at 5 ug/mL.

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  Immunofluorescence of CADM3 in mouse brain tissue with CADM3 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: CADM3 antibody was raised against a 16 amino acid peptide near the center of human CADM3.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: CADM3 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 44, 48 kDa; Observed: 44 kDa
• Gene Name: cell adhesion molecule 3
• Database Link:
  NP_001120645
  Entrez Gene 94332 MouseEntrez Gene 360882 RatEntrez Gene 57863 Human
  UniProt ID Q8N126
• Background: Cell adhesion molecule 3 (CADM3) is a member of a family of immunoglobulin-like, calcium-independent cell-cell adhesion molecules (1,2). CADM3 localizes to non-junctional contact sites of presynaptic nerve terminals, axons and glia cell processes and is thought to play an important role in the formation of synapses, axon bundles and myelinated axons (3). Recently, CADM3 has been shown to suppress the growth and tumorigenic ability of colon cancer cells, indicating that it can act as a tumor suppressor (4).
• Synonyms: BIgR; IGSF4B; Necl-1; NECL1; synCAM3; TSLL1

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs)