alpha Synuclein (SNCA) Rabbit Polyclonal Antibody

CAT#: TA349164

Rabbit Polyclonal Anti-SNRPN Antibody

Product Images

Western blot analysis of SNRPN in THP-1 cell lysate with SNRPN antibody at (A) 0.5 and (B) 1 ug/mL.

• 

  Immunohistochemistry of SNRPN in human spleen tissue with SNRPN antibody at 5 ug/mL.

• 

  Immunofluorescence of SNRPN in human spleen tissue with SNRPN antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 0.5 - 1 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: SNRPN antibody was raised against a 20 amino acid peptide near the amino terminus of human SNRPN.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: SNRPN antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 26 kDa; Observed: 25 kDa
• Gene Name: synuclein alpha
• Database Link:
  NP_000336
  Entrez Gene 20617 MouseEntrez Gene 29219 RatEntrez Gene 6622 Human
  UniProt ID P37840
• Background: The small nuclear riboprotein-associated protein N (SNRPN) is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. SNRPN plays a role in pre-mRNA processing and alternative splicing (1). SNRPN arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF) (2). Mutations or deletions in the SNRPN gene may be linked to responsible for Angelman syndrome or Prader-Willi syndrome (3).
• Synonyms: NACP; PARK1; PARK4; PD1

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Alzheimer's disease, Parkinson's disease