ARHI (DIRAS3) Rabbit Polyclonal Antibody

CAT#: TA349188

Rabbit Polyclonal Anti-S1PR2 Antibody

Product Images

Western blot analysis of S1PR2 in HeLa cell lysate with S1PR2 antibody at 1 ug/mL.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: S1PR2 antibody was raised against an 16 amino acid peptide near the carboxy terminus of human S1PR2.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: S1PR2 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 39 kDa; Observed: 50 kDa
• Gene Name: DIRAS family GTPase 3
• Database Link:
  NP_004666
  Entrez Gene 9077 Human
  UniProt ID O95661
• Background: The Sphingosine 1-phosphate receptor 2 (S1PR2) protein was initially identified as G-protein coupled receptor thought to be involved in development (1) and was found to mediate sphingosine 1-phosphate (SPP)-induced cell rounding and neurite retraction (2). S1PR2 and the related protein S1PR3 (also known as EDG3) are also thought to mediate the SPP-induced cell proliferation, survival, and related signaling events (3). S1PR2 has also been found to be key regulator in acute vascular inflammation and may be a novel therapeutic target for vascular disorders (4).
• Synonyms: ARHI; NOEY2