RAGE (AGER) Rabbit Polyclonal Antibody

CAT#: TA349215

Rabbit Polyclonal Anti-AGER Antibody

Product Images

Gel: 8%SDS-PAGE, Lysate: 40 ug, Primary antibody: (AGER Antibody) at dilution 1/750 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes

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  The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using (AGER Antibody) at dilution 1/70. (Original magnification: ×200)

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  The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using (AGER Antibody) at dilution 1/70. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 2000-5000, WB: 500-2000, IHC: 100-300
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human AGER
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 43 kDa
• Gene Name: advanced glycosylation end product-specific receptor
• Database Link:
  NP_001127
  Entrez Gene 177 Human
  UniProt ID Q15109
• Background: The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene.
• Synonyms: RAGE

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane