SAR1B Rabbit Polyclonal Antibody

CAT#: TA349246

Rabbit Polyclonal Anti-SAR1B Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA349246 (SAR1B Antibody) at dilution 1/20. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA349246 (SAR1B Antibody) at dilution 1/20. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human thyroid cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human SAR1B
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: secretion associated Ras related GTPase 1B
• Database Link:
  NP_057187
  Entrez Gene 66397 MouseEntrez Gene 287276 RatEntrez Gene 51128 Human
  UniProt ID Q9Y6B6
• Background: The protein encoded by this gene is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene.
• Synonyms: ANDD; CMRD; GTBPB; SARA2