CLDND1 Rabbit Polyclonal Antibody

CAT#: TA349283

Rabbit Polyclonal Anti-CLDND1 Antibody

Product Images

Gel: 12%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Hepg2 cells, K562 cells, Primary antibody: (CLDND1 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes

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  The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using (CLDND1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)

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  The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using (CLDND1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 2000-5000, WB: 200-1000, IHC: 50-200
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human CLDND1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 29 kDa
• Gene Name: claudin domain containing 1
• Database Link:
  NP_063948
  Entrez Gene 224250 MouseEntrez Gene 56650 Human
  UniProt ID Q9NY35
• Background: CLDND1 (claudin domain containing 1), also known as C3orf4 or HSPC174, is a 253 amino acid multi-pass membrane protein that is expressed at high levels in adult brain and at lower levels in adult heart. Existing as two alternatively spliced isoforms, CLDND1 is encoded by a gene that maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
• Synonyms: C3orf4; GENX-3745

Reference Data

• Protein Families: Transmembrane