FGL1 Rabbit Polyclonal Antibody

CAT#: TA349318

Rabbit Polyclonal Anti-FGL1 Antibody

Product Images

Gel: 15%SDS-PAGE Lysate: 40 μg Lane: Human fetal liver tissue Primary antibody: TA349318 (FGL1 Antibody) at dilution 1/500 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 2 seconds

• 

  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA349318 (FGL1 Antibody) at dilution 1/50 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA349318 (FGL1 Antibody) at dilution 1/50, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Human fetal liver tissue
  IHC: 50-200
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human FGL1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 36 kDa
• Gene Name: fibrinogen like 1
• Database Link:
  NP_963846
  Entrez Gene 234199 MouseEntrez Gene 246186 RatEntrez Gene 2267 Human
  UniProt ID Q08830
• Background: Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene.
• Synonyms: HFREP1; HP-041; LFIRE-1; LFIRE1

Reference Data

• Protein Families: Druggable Genome, Secreted Protein