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Hsp22 (HSPB8) Rabbit Polyclonal Antibody
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Transient overexpression lysate of heat shock 22kDa protein 8 (HSPB8)
USD 396.00
Other products for "HSPB8"
Specifications
| Product Data | |
| Applications | IHC |
| Recommended Dilution | IHC: 50-200 Positive control: Human cervical cancer Predicted cell location: Cytoplasm |
| Reactivities | Human, Mouse, Rat |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human HSPB8 |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Gene Name | heat shock protein family B (small) member 8 |
| Database Link | |
| Background | The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. |
| Synonyms | CMT2L; DHMN2; E2IG1; H11; HMN2; HMN2A; HSP22 |
| Reference Data | |
| Protein Families | Druggable Genome, Protein Kinase |
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