IGSF8 Rabbit Polyclonal Antibody

CAT#: TA349350

Rabbit Polyclonal Anti-IGSF8 Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human brain tissue using TA349350 (IGSF8 Antibody) at dilution 1/15 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA349350 (IGSF8 Antibody) at dilution 1/15, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 15-50
  Positive control: Human brain
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human IGSF8
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: immunoglobulin superfamily member 8
• Database Link:
  NP_443100
  Entrez Gene 140559 MouseEntrez Gene 93185 Human
  UniProt ID Q969P0
• Background: This gene encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain, an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains. This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. The encoded protein may also function as a tumor suppressor by inhibiting the proliferation of certain cancers. Alternate splicing results in multiple transcript variants that encode the same protein.
• Synonyms: CD81P3; CD316; EWI-2; EWI2; KCT-4; LIR-D1; PGRL

Reference Data

• Protein Families: Transmembrane