IRF6 Rabbit Polyclonal Antibody

CAT#: TA349362

Rabbit Polyclonal Anti-IRF6 Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-3: 231 cells mouse kidney tissue Mouse lung tissue Primary antibody: TA349362 (IRF6 Antibody) at dilution 1/400 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 5 minutes

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  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA349362 (IRF6 Antibody) at dilution 1/50 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA349362 (IRF6 Antibody) at dilution 1/50, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA349362 (IRF6 Antibody) at dilution 1/50 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA349362 (IRF6 Antibody) at dilution 1/50, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: 231 cells, mouse kidney and lung tissue
  IHC: 50-200
  Positive control: Human cervical cancer
  Predicted cell location: Nucleus and Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human IRF6
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 53 kDa
• Gene Name: interferon regulatory factor 6
• Database Link:
  NP_006138
  Entrez Gene 54139 MouseEntrez Gene 3664 Human
  UniProt ID O14896
• Background: This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.
• Synonyms: LPS; OFC6; PIT; PPS; PPS1; VWS; VWS1

Reference Data

• Protein Families: ES Cell Differentiation/IPS, Transcription Factors