SYT17 Rabbit Polyclonal Antibody

CAT#: TA349444

Rabbit Polyclonal Anti-SYT17 Antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane: Mouse kidney tissue Primary antibody: TA349444 (SYT17 Antibody) at dilution 1/650 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute

• 

  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA349444 (SYT17 Antibody) at dilution 1/60 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA349444 (SYT17 Antibody) at dilution 1/60, treated with fusion protein. (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA349444 (SYT17 Antibody) at dilution 1/60 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA349444 (SYT17 Antibody) at dilution 1/60, treated with fusion protein. (Original magnification: ×200)

Show all 5 images

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Mouse kidney tissue
  IHC: 50-200
  Positive control: Human cervical cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human SYT17
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 54 kDa
• Gene Name: synaptotagmin 17
• Database Link:
  NP_057608
  Entrez Gene 110058 MouseEntrez Gene 192189 RatEntrez Gene 51760 Human
  UniProt ID Q9BSW7
• Background: Synaptotagmin XVII (SytXVII), also known as Synaptotagmin-17 (SYT17) or Protein B/K, is a 474 amino acid peripheral membrane protein that belongs to the Synaptotagmin family and contains two C2 domains. While expressed abundantly in brain (frontal and temporal lobes, hippocampus, hypothalamus, amygdala, substantia nigra and pituitary), kidney and prostate, Synaptotagmin XVII is also expressed in fetal brain, kidney and lung. The gene that encodes Synaptotagmin XVII contains 100,082 bases and maps to human chromosome 16p12.3. Encoding over 900 genes and consisting of approximately 90 million base pairs, chromosome 16 makes up nearly 3% of the human genome and is associated with a variety of genetic disorders, such as giant axonal neuropathy, Rubinstein-Taybi syndrome and Crohn's disease. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.
• Synonyms: sytXVII