Amphiregulin (AREG) Rabbit Polyclonal Antibody

CAT#: TA349466

Rabbit Polyclonal Anti-AREG Antibody

Product Images

Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-3: HepG2 cells, Hela cells, 231 cells, Primary antibody: (AREG Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 15 seconds

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 2000-5000, WB: 500-2000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human AREG
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 28 kDa
• Gene Name: amphiregulin
• Database Link:
  NP_001648
  Entrez Gene 374 Human
  UniProt ID P15514
• Background: The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. This encoded protein is associated with a psoriasis-like skin phenotype
• Synonyms: AR; AREGB; CRDGF; SDGF

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: ErbB signaling pathway