CRM1 (XPO1) Rabbit Polyclonal Antibody

CAT#: TA349641

Rabbit Polyclonal Anti-XPO1 Antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane: NIH/3T3 cells Primary antibody: TA349641 (XPO1 Antibody) at dilution 1/275 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA349641 (XPO1 Antibody) at dilution 1/25 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA349641 (XPO1 Antibody) at dilution 1/25, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: NIH/3T3 cells
  IHC: 25-100
  Positive control: Human thyroid cancer
  Predicted cell location: Cytoplasm and Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human XPO1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 124 kDa
• Gene Name: exportin 1
• Database Link:
  NP_003391
  Entrez Gene 85252 RatEntrez Gene 103573 MouseEntrez Gene 7514 Human
  UniProt ID O14980
• Background: The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.
• Synonyms: CRM1; emb; exp1

Reference Data

• Protein Families: Druggable Genome