CABLES1 Rabbit Polyclonal Antibody

CAT#: TA349729

Rabbit Polyclonal Anti-CABLES1 Antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane 1-3: Mouse brain tissue Mouse heart tissue mouse liver tissue Primary antibody: TA349729 (CABLES1 Antibody) at dilution 1/350 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute

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  Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using TA349729 (CABLES1 Antibody) at dilution 1/15 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using TA349729 (CABLES1 Antibody) at dilution 1/15, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA349729 (CABLES1 Antibody) at dilution 1/15 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA349729 (CABLES1 Antibody) at dilution 1/15, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Mouse brain and heart tissue, mouse liver tissue
  IHC: 25-100
  Positive control: Human prostate cancer
  Predicted cell location: Nucleus and Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human CABLES1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 68 kDa
• Gene Name: Cdk5 and Abl enzyme substrate 1
• Database Link:
  NP_612384
  Entrez Gene 63955 MouseEntrez Gene 91768 Human
  UniProt ID Q8TDN4
• Background: This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene.
• Synonyms: CABL1; CABLES; HsT2563; IK3-1