CST6 Rabbit Polyclonal Antibody

CAT#: TA349860

Rabbit Polyclonal Anti-CST6 Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human brain tissue using TA349860 (CST6 Antibody) at dilution 1/70 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA349860 (CST6 Antibody) at dilution 1/70, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA349860 (CST6 Antibody) at dilution 1/70 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA349860 (CST6 Antibody) at dilution 1/70, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 100-300
  Positive control: Human brain
  Predicted cell location: Cytoplasm
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human CST6
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: cystatin E/M
• Database Link:
  NP_001314
  Entrez Gene 1474 Human
  UniProt ID Q15828
• Background: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. This gene encodes a cystatin from the type 2 family, which is down-regulated in metastatic breast tumor cells as compared to primary tumor cells. Loss of expression is likely associated with the progression of a primary tumor to a metastatic phenotype.
• Synonyms: cystatin 6; cystatin E; cystatin M; cysteine proteinase inhibitor; E; M

Reference Data

• Protein Families: Secreted Protein