Kallikrein 6 (KLK6) Rabbit Polyclonal Antibody

CAT#: TA350122

Rabbit Polyclonal Anti-KLK6 Antibody


USD 345.00

In Stock*

Size
    • 100 ul

Other products for "KLK6"

Specifications

Product Data
Applications IHC, WB
Recommended Dilution WB: 500-2000
WB positive control: A375 cells
IHC: 100-300
Positive control: Human colon cancer
Predicted cell location: Cytoplasm
Reactivities Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein of human KLK6
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 27 kDa
Gene Name kallikrein related peptidase 6
Background Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.
Synonyms Bssp; hK6; Klk7; PRSS9; PRSS18; SP59
Reference Data
Protein Families Druggable Genome, Protease, Secreted Protein

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