PAICS Rabbit Polyclonal Antibody

CAT#: TA350264

Rabbit Polyclonal Anti-PAICS Antibody


USD 345.00

In Stock*

Size
    • 100 ul

Other products for "PAICS"

Specifications

Product Data
Applications IHC, WB
Recommended Dilution WB: 500-2000
WB positive control: Hela, K562, Raji and Jurkat cells
IHC: 50-200
Positive control: Human cervical cancer
Predicted cell location: Cytoplasm or Cell membrane
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein of human PAICS
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 47 kDa
Gene Name phosphoribosylaminoimidazole carboxylase; phosphoribosylaminoimidazolesuccinocarboxamide synthase
Background This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms ADE2; ADE2H1; AIRC; PAIS
Reference Data
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Purine metabolism

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