SIGLECL1 (SIGLEC12) Rabbit Polyclonal Antibody

CAT#: TA350415

Rabbit Polyclonal Anti-SIGLEC12 rabbit polyclonal antibody

Product Images

Gel: 8%SDS-PAGE, Lysate: 40 ug, Primary antibody: (SIGLEC12 Antibody) at dilution 1/500 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute

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  The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using (SIGLEC12 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1000-2000, WB: 200-1000, IHC: 25-100
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human SIGLEC12
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 65 kDa
• Gene Name: sialic acid binding Ig like lectin 12 (gene/pseudogene)
• Database Link:
  NP_443729
  Entrez Gene 89858 Human
  UniProt ID Q96PQ1
• Background: Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to the immunoglobulin superfamily. They mediate protein-carbohydrate interactions by selectively binding to different sialic acid moieties present on glycolipids and glycoproteins. This gene encodes a member of the SIGLEC3-like subfamily of SIGLECs. Members of this subfamily are characterized by an extracellular V-set immunoglobulin-like domain followed by two C2-set immunoglobulin-like domains, and the cytoplasmic tyrosine-based motifs ITIM and SLAM-like.
• Synonyms: S2V; Siglec-XII; SIGLECL1; SLG

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency, Transmembrane