CRMP4 (DPYSL3) Rabbit Polyclonal Antibody

CAT#: TA350641

Rabbit Polyclonal Anti-DPYSL3 Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane: Mouse heart tissue lysate Primary antibody: TA350641 (DPYSL3 Antibody) at dilution 1/400 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 20 seconds

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA350641 (DPYSL3 Antibody) at dilution 1/20 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA350641 (DPYSL3 Antibody) at dilution 1/20, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Mouse heart tissue lysate
  IHC: 25-50
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human DPYSL3
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 62 kDa
• Gene Name: dihydropyrimidinase like 3
• Database Link:
  NP_001378
  Entrez Gene 22240 MouseEntrez Gene 25418 RatEntrez Gene 1809 Human
  UniProt ID Q14195
• Background: Collapsin response mediator proteins (CRMPs), including CRMP-1 (DRP-1), CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-4 (DRP-3) and CRMP-5 (DRP-5), mediate signal transduction after exposure of neural cells to the axon guidance molecule semaphorin 3A (SEMA3A)/collapsin. CRMPs are present in the developing cerebral cortex and neocortical neurons and are responsive to SEMA3A. In the adult brain, the expression of CRMPs is dramatically downregulated. However, they remain expressed in structures that retain their capacity for differentiation and plasticity. Developing neurons in the adult hippocampus of mammals, known as the dentate gyrus, express CRMP-4. Rodent neocortical neurons express CRMP-4 in the perikaryon, in neurites and at growth cones.
• Synonyms: CRMP-4; CRMP4; DRP-3; DRP3; LCRMP; ULIP; ULIP-1