Dopamine Transporter (SLC6A3) Rabbit Polyclonal Antibody

CAT#: TA350649

Rabbit Polyclonal Anti-SLC6A3 Antibody

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 100-300
  Positive control: Human tonsil
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human SLC6A3
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: solute carrier family 6 member 3
• Database Link:
  NP_001035
  Entrez Gene 13162 MouseEntrez Gene 24898 RatEntrez Gene 6531 Human
  UniProt ID Q01959
• Background: This gene encodes a dopamine transporter which is a member of the sodium- and chloride-dependent neurotransmitter transporter family. The 3' UTR of this gene contains a 40 bp tandem repeat, referred to as a variable number tandem repeat or VNTR, which can be present in 3 to 11 copies. Variation in the number of repeats is associated with idiopathic epilepsy, attention-deficit hyperactivity disorder, dependence on alcohol and cocaine, susceptibility to Parkinson disease and protection against nicotine dependence.
• Synonyms: DAT; DAT1; PKDYS

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Parkinson's disease