STK3 Rabbit Polyclonal Antibody

CAT#: TA351035

Rabbit Polyclonal Anti-STK3/STK4 Antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane 1-5: PC3 cells hela cells human bladder carcinoma tissue A172 cells hepG2 cells Primary antibody: TA351035 (STK3/STK4 Antibody) at dilution 1/1000 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 10 seconds

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  Immunohistochemistry of paraffin-embedded Human Lymphoma tissue using TA351035 (STK3/STK4 Antibody) at dilution 1/70 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human Lymphoma tissue using TA351035 (STK3/STK4 Antibody) at dilution 1/70, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA351035 (STK3/STK4 Antibody) at dilution 1/70 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA351035 (STK3/STK4 Antibody) at dilution 1/70, treated with synthetic peptide. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: HepG2 cells
  IHC: 50-200
  Positive control: Human Lymphoma
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human STK3/STK4
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 56 kDa
• Gene Name: serine/threonine kinase 3
• Database Link:
  NP_006272
  Entrez Gene 56274 MouseEntrez Gene 6788 Human
  UniProt ID Q13188
• Background: Sterile-20 (Ste20) is a serine/threonine kinase in Saccharomyces cerevisiae that is involved in relaying signals from G protein-coupled receptors to cyto-solic MAP kinase cascades. Mammalian protein kinases that display sequence similarity to Ste20 are divided into two groups, the PAK subfamily and the GCK subfamily. The mammalian Ste20-like kinases (MST kinases), also known as Krs proteins, are members of the GCK subfamily. Ksr-1 (MST-2) and Ksr-2 (MST-1) are both direct substrates of caspase-3 that accelerate caspase-3 activation.
• Synonyms: KRS1; MST2

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: MAPK signaling pathway