NCR1 Rabbit Polyclonal Antibody

CAT#: TA351045

Rabbit Polyclonal Anti-NCR1 Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane: A549 cell lysate Primary antibody: TA351045 (NCR1 Antibody) at dilution 1/550 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 1 minute

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA351045 (NCR1 Antibody) at dilution 1/50 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA351045 (NCR1 Antibody) at dilution 1/50, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA351045 (NCR1 Antibody) at dilution 1/50 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA351045 (NCR1 Antibody) at dilution 1/50, treated with synthetic peptide. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Human plasma solution
  IHC: 50-300
  Positive control: Human liver cancer
  Predicted cell location: Secreted and Cell membrane
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human NCR1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 34 kDa
• Gene Name: natural cytotoxicity triggering receptor 1
• Database Link:
  NP_004820
  Entrez Gene 9437 Human
  UniProt ID O76036
• Background: Natural cytotoxicity triggering receptor 1 is a protein that in humans is encoded by the NCR1 gene. NCR1 has also been designated as CD335 (cluster of differentiation 335). Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Interacts with CD247 and FCER1G. Selectively expressed by both resting and activated NK cells.
• Synonyms: CD335; LY94; NK-p46; NKP46

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Natural killer cell mediated cytotoxicity