ETS1 associated protein II (TDP2) Rabbit Polyclonal Antibody

CAT#: TA351171

Rabbit Polyclonal Anti-TDP2 Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane: Mouse small intestines tissue lysate Primary antibody: TA351171 (TDP2 Antibody) at dilution 1/600 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 90 seconds

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  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA351171 (TDP2 Antibody) at dilution 1/75 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA351171 (TDP2 Antibody) at dilution 1/75, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA351171 (TDP2 Antibody) at dilution 1/75 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA351171 (TDP2 Antibody) at dilution 1/75, treated with synthetic peptide. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC: 25-100
  Positive control: Human cervical cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human TDP2
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 41 kDa
• Gene Name: tyrosyl-DNA phosphodiesterase 2
• Database Link:
  NP_057698
  Entrez Gene 56196 MouseEntrez Gene 51567 Human
  UniProt ID O95551
• Background: This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.
• Synonyms: AD022; dJ30M3.3; EAP2; EAPII; hTDP2; TTRAP

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency, Transcription Factors