GABA A Receptor alpha 1 (GABRA1) Rabbit Polyclonal Antibody

CAT#: TA351205

Rabbit Polyclonal Anti-GABRA1 Antibody


USD 345.00

In Stock*

Size
    • 100 ul

Other products for "GABRA1"

Specifications

Product Data
Applications IHC, WB
Recommended Dilution IHC: 50-200
Positive control: Human thyroid cancer
Predicted cell location: Cytoplasm
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide of human GABRA1
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 52 kDa
Gene Name gamma-aminobutyric acid type A receptor alpha1 subunit
Background This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene
Synonyms ECA4; EIEE19; EJM; EJM5
Reference Data
Protein Families Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane
Protein Pathways Neuroactive ligand-receptor interaction

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