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MRGX1 (MRGPRX1) Rabbit Polyclonal Antibody
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Other products for "MRGPRX1"
Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommended Dilution | IHC: 25-100 Positive control: Human brain Predicted cell location: Cytoplasm and Nucleus |
| Reactivities | Human, Mouse |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human MRGPRX1 |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Gene Name | MAS related GPR family member X1 |
| Database Link | |
| Background | MRGX1 is an opiod receptor that has been reported exclusively in dorsal root ganglion. MRGX1 is probably involved in the function of nociceptive neurons and may regulate nociceptor function and/or development, including the sensation or modulation of pain. It is potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. |
| Synonyms | GPCR; MGRG2; MRGX1; SNSR4 |
| Reference Data | |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
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