SGPL1 Rabbit Polyclonal Antibody

CAT#: TA351661

Rabbit Polyclonal Anti-SGPL1 Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane: Human placenta tissue Primary antibody: TA351661 (SGPL1 Antibody) at dilution 1/200 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 second

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  Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TA351661 (SGPL1 Antibody) at dilution 1/40 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TA351661 (SGPL1 Antibody) at dilution 1/40, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA351661 (SGPL1 Antibody) at dilution 1/40 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA351661 (SGPL1 Antibody) at dilution 1/40, treated with synthetic peptide. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Human placenta tissue
  IHC: 25-100
  Positive control: Human breast cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human SGPL1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 64 kDa
• Gene Name: sphingosine-1-phosphate lyase 1
• Database Link:
  NP_003892
  Entrez Gene 20397 MouseEntrez Gene 286896 RatEntrez Gene 8879 Human
  UniProt ID O95470
• Background: Sphingosine-1-phosphate lyase 1 is an enzyme that in humans is encoded by the SGPL1gene. Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis.
• Synonyms: S1PL; SPL

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Sphingolipid metabolism