SLC17A1 Rabbit Polyclonal Antibody

CAT#: TA351718

Rabbit Polyclonal Anti-SLC17A1 rabbit polyclonal antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Human kidney cancer and kidney pericarcinous tissue
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human SLC17A1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 51 kDa
• Gene Name: solute carrier family 17 member 1
• Database Link:
  NP_005065
  Entrez Gene 6568 Human
  UniProt ID Q14916
• Background: NPT1, also called sodium-dependent phosphate transport protein, belongs to the organic anion transporter family, SLC17A. It is mainly expressed in the kidney transporting small organic anions such as PAH (para-aminohippurate), but it is also found in the liver and brain. NTP1 localizes to the apical membrane of renal proximal tubular cells and functions as a voltage driven organic anion/Cl-exchanger. It also plays a role in maintaining phosphate homeostasis. The expression of NPT1 is transcriptionally regulated by HNF-1å and HNF-3∫. Indomethacin and salicylate inhibit NPT1-mediated PAH transport.
• Synonyms: NAPI-1; NPT-1; NPT1

Reference Data

• Protein Families: Transmembrane