KCNK3 Rabbit Polyclonal Antibody

CAT#: TA351788

Rabbit Polyclonal Anti-KCNK3 Antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Mouse heart tissue
  IHC: 10-50
  Positive control: Human brain
  Predicted cell location: Cytoplasm and Cell membrane
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human KCNK3
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 45 kDa
• Gene Name: potassium two pore domain channel subfamily K member 3
• Database Link:
  NP_002237
  Entrez Gene 16527 MouseEntrez Gene 29553 RatEntrez Gene 3777 Human
  UniProt ID O14649
• Background: TASK channels are highly sensitive to external pH in the physiological range. TASK-1 is expressed in brain and in rat heart, with high levels of expression in the right atrium. TASK-2, mainly expressed in kidney, is localized in cortical distal tubules and collecting ducts, suggesting a role in renal K+ transport. TASK-3 from rat cerebellum shares 54% identity with TASK-1, but less than 30% identity with TASK-2 and other tandem pore K+ channels.
• Synonyms: K2p3.1; OAT1; PPH4; TASK; TASK-1; TBAK1

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Potassium, Transmembrane