Topoisomerase II beta (TOP2B) Rabbit Polyclonal Antibody

CAT#: TA351833

Rabbit Polyclonal Anti-TOP2B Antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane 1-4: Raw264.7 Jurkat cells K562 cells hepg2 cells Primary antibody: TA351833 (TOP2B Antibody) at dilution 1/250 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 40 seconds

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Raw264.7, Jurkat, K562 and hepg2 cells
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human TOP2B
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 183 kDa
• Gene Name: topoisomerase (DNA) II beta
• Database Link:
  NP_001059
  Entrez Gene 21974 MouseEntrez Gene 7155 Human
  UniProt ID Q02880
• Background: This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA.
• Synonyms: top2beta; TOPIIB

Reference Data

• Protein Families: Druggable Genome