TPD52 Rabbit Polyclonal Antibody

CAT#: TA351837

Rabbit Polyclonal Anti-TPD52 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Raji, 231, 293T and A549 cells
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human TPD52
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 24 kDa
• Gene Name: tumor protein D52
• Database Link:
  NP_005070
  Entrez Gene 7163 Human
  UniProt ID P55327
• Background: The tumor protein D52 (TPD52) family consists of three members, TPD52, TPD52L1 (D53), and TPD52L2 (D54). These small coiled-coil motif bearing proteins interact in hetero- and homomeric fashion. The TPD52 gene maps to chromosome 8q21, and due to amplification, shows frequent overexpression in prostate and breast carcinomas. TPD52 bound to annexin VI in a Ca(2+)-dependent manner, suggesting that these molecules may act in concert to regulate secretory processes in plasma cells.
• Synonyms: D52; hD52; N8L; PC-1; PrLZ