CTIP1 (BCL11A) Mouse Monoclonal Antibody [Clone ID: BCL11A/123]

CAT#: TA352998L

Mouse monoclonal Anti-BCL11A Clone BCL11A/123

Specifications

Product Data

• Clone Name: BCL11A/123
• Recommended Dilution: IHC ; IP ; WB
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: C-terminus of extra long isoform of BCL11A, BCL11AXL (aa 637-835)
• Formulation: PBS with 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted 91 kDa
• Gene Name: B-cell CLL/lymphoma 11A
• Database Link:
  NP_612569
  Entrez Gene 53335 Human
  UniProt ID Q9H165
• Background: BCL11A is a Krüppel zinc-finger transcription factor that was identified originally from a chromosome translocation in aggressive B-cell chronic lymphocytic leukaemia. The gene may function as both an oncogene and a tumour suppressor. Alternative splicing generates multiple isoforms, the BCL11AXL being the largest and most abundant transcript. The protein is differentially expressed during B-cell development and is strongly expressed in plasmacytoid dendritic cells. The BCL11A/123 antibody specifically recognises the extra long form of the protein and not the long or short forms of BCL11A. The BCL11A/123 antibody is not cross reactive with the long form of the BCL11B protein that shares significant sequence identity with the immunogen.
• Synonyms: BCL11A-L; BCL11a-M; BCL11A-S; BCL11A-XL; CTIP1; DILOS; EVI9; HBFQTL5; ZNF856
• Note: IHC: Frozen use neat supernatant

Reference Data

• Protein Families: Transcription Factors