BLK Mouse Monoclonal Antibody [Clone ID: BLK154/D4]

CAT#: TA353004L

Mouse monoclonal Anti-BLK Clone BLK154/D4

Specifications

Product Data

• Clone Name: BLK154/D4
• Recommended Dilution: WB
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant protein corresponding to amino acids 53- 224 of human BLK
• Formulation: PBS with 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: BLK proto-oncogene, Src family tyrosine kinase
• Database Link:
  NP_001706
  Entrez Gene 640 Human
  UniProt ID P51451
• Background: B lymphoid tyrosine kinase is a member of the src family of proto-oncogenes that are involved in cell proliferation and differentiation1. It is expressed in B cells during all stages of development and has a role in B-cell receptor signaling and B-cell development2,3. BLK also stimulates insulin synthesis and secretion in response to glucose by up regulating pancreatic beta-cell transcription factors.
• Synonyms: MODY11

Reference Data

• Protein Families: Druggable Genome, Protein Kinase