Annexin IV (ANXA4) Rabbit Polyclonal Antibody

CAT#: TA354173

Rabbit anti Annexin IV Polyclonal Antibody

Product Images

WB: Whole tissue lysate derived from mouse kidney was resolved onto 12% SDS-PAGE, transferred onto NC membrane, then immuneprobed by anti-Annexin IV antibody (Lane 1) or pre-depleted antibody by the immunizing peptide (lane 2) at 1:500. The immune-reactive band around ~34kDa was abolished.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide corresponding to the N-terminus of human Annexin IV. This sequence is identical to human, mouse and rat.
• Formulation: This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
• Purification: The Rabbit IgG is purified by Epitope Affinity Purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: ~34 kDa
• Gene Name: annexin A4
• Database Link:
  NP_001144
  Entrez Gene 11746 MouseEntrez Gene 79124 RatEntrez Gene 307 Human
  UniProt ID P09525
• Background: The annexins are a family of highly homologous Calcium and phospholipid binding proteins. It is composed of at least ten mammalian genes. It is characterized by a conserved core domain which binds to phospholipids in a Ca2+ dependent manner and a unique amino terminal region which may confer binding specificity. Annexin family members have been implicated as regulators of such diverse processes as ion flux, endocytosis/exocytosis and cellular adhesion, Annexin IV, also referred to as endonexin, functions to regulate Cl—flux by mediating calmodulin kinase II (CaMKII) activity while Annexin V has been shown to regulate PKC activity. The expressive amounts of several annexins have been shown to alter in certain pathological states such as brain ischemia and Alzheimer's disease.
• Synonyms: ANX4; HEL-S-274; PIG28; ZAP36