Plastin L (LCP1) Rabbit Polyclonal Antibody

CAT#: TA354533

Rabbit anti L-Plastin Polyclonal Antibody

Specifications

Product Data

• Recommended Dilution: WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide corresponding to the C-terminus of human L-plastin protein. This sequence is identical to rat, mouse and human origins.
• Formulation: This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
• Purification: The Rabbit IgG is purified by Epitope Affinity Purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: ~70 kDa
• Gene Name: lymphocyte cytosolic protein 1
• Database Link:
  NP_002289
  Entrez Gene 18826 MouseEntrez Gene 306071 RatEntrez Gene 3936 Human
  UniProt ID P13796
• Background: L-plastin is a protein normally found in leukocytes (white blood cells) only. In these cells L-plastin regulates cell movement by interacting with actins, a major cellular protein that directly controls cell movement. Normal breast epithelial cells do not have L-plastin. It only presents in breast carcinoma cells. Furthermore, the amount of L-plastin contained in the cells correlates with the degree of invasiveness of these cells. Therefore, it appears that L-plastin may be important for the motility of breast cancer cells.
• Synonyms: CP64; HEL-S-37; L-PLASTIN; LC64P; LPL; PLS2