AMACR Mouse Monoclonal Antibody [Clone ID: EPMU1]

CAT#: TA355219

Alpha-Methylacyl-CoA Racemase (AMACR, p504s) Mouse Monoclonal Antibody

Specifications

Product Data

• Clone Name: EPMU1
• Applications: IHC
• Recommended Dilution: 1:200
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Prokaryotic recombinant protein corresponding to 382 amino acids of the human alpha-methylacyl-CoA racemase molecule
• Specificity: Human alpha-methylacyl-CoA racemase
• Formulation: Liquid tissue culture supernatant containing 15 mM sodium azide as a preservative
• Conjugation: Unconjugated
• Storage: Store at 2-8°C
• Stability: 12 months
• Gene Name: alpha-methylacyl-CoA racemase
• Database Link:
  Entrez Gene 23600 Human
• Background: Alpha-methylacyl-CoA racemase (AMACR), also known as p504s, is a mitochondrial and peroxisomal enzyme that is involved in bile acid biosynthesis and beta-oxidation of branched-chain fatty acids. AMACR is essential in lipid metabolism, and is expressed in normal liver (hepatocytes), kidney (tubular epithelial cells) and gall bladder (epithelial cells). Expression has also been found in lung (bronchial epithelial cells) and colon (colonic surface epithelium). Expression is granular and cytoplasmic. AMACR expression can also be found in hepatocellular carcinoma and kidney carcinoma. Past studies have also shown that AMACR is expressed in various colon carcinomas (well, moderately and poorly differentiated) and over expressed in prostate carcinoma.
• Synonyms: CBAS4; RACE; RM