CD13 (ANPEP) Mouse Monoclonal Antibody [Clone ID: 38C12]

CAT#: TA355245

CD13 Mouse Monoclonal Antibody

Specifications

Product Data

• Clone Name: 38C12
• Applications: IHC
• Recommended Dilution: 1:80
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant prokaryotic fusion protein corresponding to the C-terminal region of the extracellular domain
• Specificity: Human CD13 antigen
• Formulation: Liquid tissue culture supernatant containing sodium azide as a preservative
• Conjugation: Unconjugated
• Storage: Store at 2-8°C
• Stability: 12 months
• Gene Name: alanyl aminopeptidase, membrane
• Database Link:
  Entrez Gene 290 Human
• Background: CD13 antigen, also known as aminopeptidase N, is a member of type II integral membrane metalloproteases, which also includes the leukocyte antigens CD10, CD26, CD73 and BP-1. CD13 antigen is a receptor for the coronaviruses which cause respiratory disease in humans and several animal species. The antigen functions as a zinc-binding metalloprotease which plays a role in cell surface antigen presentation by trimming the N-terminal amino acids from MHC class II-bound peptides. CD13 antigen is reported to be expressed on granulocytes, monocytes and their precursors, most acute myeloid leukemias and a smaller proportion of acute lymphoid leukemias. Non-hematopoietic cells which express CD13 antigen include epithelial cells, renal proximal tubules, intestinal brush border, endothelial cells, fibroblasts, brain cells, bone marrow, osteoclasts and cells lining the bile canaliculi.
• Synonyms: AP-M; AP-N; APN; CD13; GP150; hAPN; LAP1; P150; PEPN