Protein C (PROC) Mouse Monoclonal Antibody [Clone ID: 10D6]

CAT#: TA355384

PROC Antibody

Product Images

WB Suggested Anti-PROC Antibody Titration: 5 ug/ml Positive Control: ACHN Whole Cell

Specifications

Product Data

• Clone Name: 10D6
• Applications: WB
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 52
• Gene Name: protein C, inactivator of coagulation factors Va and VIIIa
• Database Link:
  NP_000303
  Entrez Gene 5624 Human
  UniProt ID P04070
• Background: This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.
• Synonyms: APC; PC; PROC1

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Complement and coagulation cascades