Choline Acetyltransferase (CHAT) Rabbit Polyclonal Antibody

CAT#: TA355459

CHAT Antibody - C-terminal region

Product Images

WB Suggested Anti-CHAT Antibody Titration: 1.0 ug/ml Positive Control: Fetal Brain

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Dog, Horse, Human, Pig
  Homology: Dog: 100%; Horse: 100%; Human: 100%; Pig: 91%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 70kDa
• Gene Name: choline O-acetyltransferase
• Database Link:
  NP_066264
  Entrez Gene 1103 Human
  UniProt ID A2BDF5
• Background: CHAT is an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This protein is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer disease. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.
• Synonyms: CHOACTase; CMS1A; CMS1A2

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Glycerophospholipid metabolism