KLF4 Rabbit Polyclonal Antibody

CAT#: TA355789

KLF4 Antibody - N-terminal region

Product Images

WB Suggested Anti-KLF4 Antibody Titration: 2.5ug/ml ELISA Titer: 1:312500 Positive Control: Transfected 293T

• 

  Human lung cell line

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KLF4
• Specificity: Expected reactivity: Cow, Dog, Horse, Human, Pig, Rabbit, Sheep
  Homology: Cow: 80%; Dog: 87%; Horse: 87%; Human: 100%; Pig: 80%; Rabbit: 85%; Sheep: 80%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Protein A purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 50kDa
• Gene Name: Kruppel-like factor 4 (gut)
• Database Link:
  NP_004226
  Entrez Gene 9314 Human
  UniProt ID O43474
• Background: The mammalian Kruppel-like transcription factor, KLF4 is involved in preventing centrosome amplification following DNA damage caused by gamma-irradiation. It is both necessary and sufficient in preventing centrosome amplification following gamma-radiation-induced DNA damage and does so by transcriptionally suppressing cyclin E expression n. Kruppel-like factor 4 is also known to exhibit checkpoint function during the G1/S and G2/M transitions of the cell cycle.
• Synonyms: EZF; GKLF

Reference Data

• Protein Families: Adult stem cells, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors