Nr1i3 Rabbit Polyclonal Antibody

CAT#: TA355926

NR1I3 Antibody - middle region

Product Images

WB Suggested Anti-NR1I3 Antibody Titration: 2.5ug/ml ELISA Titer: 1:312500 Positive Control: NIH/3T3 cell lysate

Specifications

Product Data

• Applications: WB
• Reactivities: Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse NR1I3
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Mouse, Rat
  Homology: Cow: 85%; Dog: 86%; Guinea Pig: 79%; Mouse: 93%; Rat: 93%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Protein A purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 39kDa
• Gene Name: nuclear receptor subfamily 1, group I, member 3
• Database Link:
  NP_033933
  Entrez Gene 12355 Mouse
  UniProt ID O35627
• Background: NR1I3 mediates the induction of transcription of cytochrome P450 (CYP) genes by phenobarbital (PB) and PB-type inducers. NR1I3 activation induces hepatic expression of detoxification enzymes and transporters and increases liver size. NR1I3 can also regulate both liver homeostasis and tumorigenesis in response to xenobiotic stresses.
• Synonyms: CAR; CAR1; MB67; MGC97144; MGC97209; MGC150433; OTTHUMP00000032246