KLF4 Rabbit Polyclonal Antibody

CAT#: TA355984

KLF4 Antibody - C-terminal region

Product Images

WB Suggested Anti-KLF4 Antibody Titration: 0.2-1 ug/ml Positive Control: Human heart

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  Human lung cell line

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  Host: Mouse Target Name: KLF12 Sample Tissue: Mouse Kidney Antibody Dilution: 1ug/ml

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  prostate

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  Human lung epithelial cell

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Specifications

Product Data

• Applications: IHC, WB
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human KLF4
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
  Homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 50kDa
• Gene Name: Kruppel-like factor 4 (gut)
• Database Link:
  NP_004226
  Entrez Gene 16600 MouseEntrez Gene 9314 Human
  UniProt ID O43474
• Background: The mammalian Kruppel-like transcription factor, KLF4 is involved in preventing centrosome amplification following DNA damage caused by gamma-irradiation. It is both necessary and sufficient in preventing centrosome amplification following gamma-radiation-induced DNA damage and does so by transcriptionally suppressing cyclin E expression n. Kruppel-like factor 4 is also known to exhibit checkpoint function during the G1/S and G2/M transitions of the cell cycle.
• Synonyms: EZF; GKLF

Reference Data

• Protein Families: Adult stem cells, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors